Organic metal halides
Medchemexpress LLC Tarloxotinib bromide | 1636180-98-7 | 98.75% | 681.77 | 1 ML
Tarloxotinib bromide is an irreversible EGFR/HER2 inhibitor that is efficiently metabolized under hypoxia in human NSCLC cell lines. Cellular anti-proliferative and receptor phosphorylation assays show a 14-80 fold reduction of activity relative to TKI, demonstrating greater activity compared with erlotinib. In vivo studies show that treatment with clinically relevant doses leads to tumor regression and durable inhibition of WT EGFR tumor phosphorylation, and can regress WT EGFR NSCLC tumor models H125 and H1648.
- Irreversible EGFR/HER2 inhibitor
- Efficiently metabolized under hypoxia
- Greater activity compared with erlotinib
- Associated with tumor regression and durable inhibition of WT EGFR tumor phosphorylation
- Can regress WT EGFR NSCLC tumor models H125 and H1648
Strem, An Ascensus Company CAS# 84365-55-9. 5g. Indenyltitanium trichloride, 99%. MFCD00269849
CAS# 84365-55-9. 5g. Indenyltitanium trichloride, 99%. MFCD00269849. Molecular Weight: 269.39. Molecular Formula: C9H7TiCl3. Color/form: purple xtl. Strem# 22-0950. http://www.strem.com/catalog/v/22-0950/
Medchemexpress LLC Pipecuronium (bromide) | 52212-02-9 | 99.9% | 100 MG
Pipecuronium bromide is a potent, long-acting, nondepolarizing steroidal neuromuscular blocking agent (NMBA) and a bisquaternary ammonium compound. It functions as a powerful competitive nAChR antagonist with a Kd of 3.06 μM. This product is intended for research use only and not for sale to patients.
- Potent, long-acting, nondepolarizing steroidal neuromuscular blocking agent
- Competitive nAChR antagonist with a Kd of 3.06 μM
- Solid appearance, off-white to yellow
- Molecular weight: 762.70
- Does not liberate histamine
- No cardiovascular side effects
- Anaphylaxis does not appear to be a problem
Medchemexpress LLC Pipecuronium (bromide) | 52212-02-9 | 99.9% | 1 ML
Pipecuronium bromide is a potent, long-acting nondepolarizing steroidal neuromuscular blocking agent (NMBA) and a bisquaternary ammonium compound. It acts as a powerful competitive nAChR antagonist with a Kd of 3.06 μM.
- Potent long-acting neuromuscular blocking agent.
- Acts as a powerful competitive nAChR antagonist.
- Approximately 6 to 7 times more potent than Rocuronium.
- Does not liberate histamine and has no cardiovascular side effects.
- Neuromuscular block can be reversed by carboxymethylated γ-cyclodextrin.
Medchemexpress LLC Sepantronium (bromide) | 781600-92-9 | >98% | 750.56 | 25MG
Sepantronium bromide (YM155) is a small molecule inhibitor of survivin, a member of the inhibitor of apoptosis protein (IAP) family. It exhibits potent anticancer activity by suppressing survivin expression, leading to apoptosis in various cancer cell lines.
- Small molecule inhibitor of survivin
- IC50 of 0.54 nM in a cell-free assay
- Potent anticancer activity
- Suppresses survivin expression
- Leads to apoptosis in various cancer cell lines
- Under clinical investigation for the treatment of various cancers
![eMolecules Ethylmagnesium bromide 3.0 M In diethyl ether | Oakwood Chemicals | 925-90-6 | MFCD00000043 | 133.271 | C2H5BrMg | 0.000 | [Br-].CC[Mg+] | 25ml | 480152306](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC3808380.JPG-250.jpg)
eMolecules Ethylmagnesium bromide 3.0 M In diethyl ether | Oakwood Chemicals | 925-90-6 | MFCD00000043 | 133.271 | C2H5BrMg | 0.000 | [Br-].CC[Mg+] | 25ml | 480152306
Ethylmagnesium bromide 3.0 M In diethyl ether | Oakwood Chemicals | 925-90-6 | MFCD00000043 | 133.271 | C2H5BrMg | 0.000 | [Br-].CC[Mg+] | 25ml | 480152306
Medchemexpress LLC Atropine methyl bromide | 2870-71-5 | 99.8% | 384.31 | 1 ML
Atropine methyl bromide is a muscarinic receptor (mAChR) antagonist. It is a quaternary ammonium salt of atropine that functions as a mydriatic for pupil dilation during ophthalmic examinations. Due to its highly polar nature, it is also used to relieve pyloric spasm in infants and demonstrates reduced penetration into the central nervous system compared to atropine.
- Acts as a muscarinic receptor (mAChR) antagonist
- Functions as a mydriatic for pupil dilation
- Relieves pyloric spasm in infants
- Penetrates less readily into the central nervous system
Medchemexpress LLC Pipecuronium bromide | 52212-02-9 | 99.88% | 25 MG
Pipecuronium bromide is a potent, long-acting, nondepolarizing steroidal neuromuscular blocking agent (NMBA) and a bisquaternary ammonium compound. It functions as a powerful competitive nAChR antagonist with a Kd of 3.06 μM.
- Potent and long-acting nondepolarizing steroidal neuromuscular blocking agent.
- Powerful competitive nAChR antagonist.
- Does not liberate histamine.
- No cardiovascular side effects even at doses of 3x ED95.
- Anaphylaxis does not appear to be a problem.